262 research outputs found

    Effective Three-Body Interactions in Jaynes-Cummings-Hubbard Systems

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    A generalisation of the Jaynes-Cummings-Hubbard model for coupled-cavity arrays is introduced, where the embedded two-level system in each cavity is replaced by a Ξ\Xi-type three-level system. We demonstrate that the resulting effective polariton-polariton interactions at each site are both two-body and three-body. By tuning the ratio of the two transition dipole matrix elements, we show that the strength and sign of the two-body interaction can be controlled whilst maintaining a three-body repulsion. We then proceed to demonstrate how different two-body and three-body interactions alter the mean field superfluid-Mott insulator phase diagram, with the possible emergence of a pair superfluid phase in the two-body attractive regime.Comment: 10 pages, 4 figures, accepted for publication in Scientific Reports; v3 - revised manuscrip

    A prospective cohort study to evaluate the correlates of polypharmacy and its association with depression among elderly patients

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    Background: Polypharmacy is a reliable indicator of irrational prescribing particularly among elderly. Polypharmacy increases the risk of adverse drug reactions (ADRs) exponentially imposing higher economic burden. Addressing and evaluating the prescribing practices in elderly will rationalize the drug utilization leading to improvement in quality of health care. The present study was taken to evaluate the determinants of polypharmacy and its association with depression, defined as a 15 item geriatric depression scale (GDS) >6, in elderly patients.Methods: This prospective cohort study was conducted at department of medicine, Victoria hospital, Bengaluru 100 patients aged 60 and above years was enrolled. Relevant data regarding patients’ demographic details, smoking and alcohol consumption, medical diagnosis and drug details were collected. Geriatric Depression Scale was used to diagnose depression.Results: Out of 100 patients screened, 36% were males and 64% were females. Polypharmacy was noted in 73% of the elderly, of which 43% had cumulative co morbidity (≥4 diagnoses).  68% were found to have a GDS score of ≥6, which corresponded to Depression. Patients with depression (GDS score ≥6) had 1.54 (OR-1.54, 95% CI-0.59-4.01) times more risk of encountering polypharmacy (≥4 drugs). Cumulative co-morbidity (OR-1.52, 95% CI-1.08–2.11, p <0.05) was identified as an independent correlate of polypharmacy.Conclusions: Increasing age, males, Cumulative comorbidity of ≥4 diagnoses and geriatric depression were found to be the positive correlates of polypharmacy in elderly. Though geriatric depression increases the odds of encountering polypharmacy, it does not affect drug consumption directly; rather it is an important index of cumulative co-morbidity which influences polypharmacy significantly

    Location Security -- Where to Enforce?

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    Enforcing security in location based services is very crucial in the current mobile world. Past literature has examined both location and identity obfuscation techniques in order to optimally tradeoff security/privacy with utility − this primarily addresses the ‘how to enforce location security problem’; however, it does not address the ‘where to enforce location security problem’. This paper examines the ‘where’ problem and in particular, examines tradeoffs between enforcing location security at a device vs. enforcing location security at an edge location server. This paper also sketches an implementation of location security solutions at both the device and the edge location server and presents detailed experiments using real mobility and user profile data sets collected from various data sources (taxicabs, Smartphones). Our results show that while device-based solutions do not require trust in the edge location server, they either suffer from high false positive rate (about 25% probability of not meeting the desired security requirement) or low utility (about 600 meters higher error in obfuscated location data)
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